Obese mice that lost weight on a low-fat diet before getting a flu shot had better immune responses than those that lost weight afterwards, suggesting diet and weight loss influence vaccine efficacy
By Grace Wade
24 April 2024
After mice ate a low-fat diet, their flu vaccinations were more effective iStockphoto/Getty
Switching obese mice to a lower-fat diet before flu vaccination, but not afterwards, improves their ability to fight the virus. This suggests the flu shot may be more effective in people with obesity if they lose weight or eat a different diet beforehand.
Even with immunisation, people with obesity are nearly twice as likely to get the flu than those without it. They are also…
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